Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Jul;32(3):408-17.
doi: 10.4103/0974-8520.93925.

A progressive review of Sandhana kalpana (Biomedical fermentation): An advanced innovative dosage form of Ayurveda

Anand Chaudhary  1 , Neetu Singh, Madhuri Dalvi, Asmita Wele
Affiliations

A progressive review of Sandhana kalpana (Biomedical fermentation): An advanced innovative dosage form of Ayurveda

Anand Chaudhary et al. Ayu. 2011 Jul.

Abstract

Sandhana kalpana (biomedical fermented formulations) are one of the best dosage forms of Ayurveda in practice since thousands of years. In order to prepare these medicaments, certain sets of conditions are prearranged, which lead to fermentation. Thus, products bequeath with self-generated ethyl alcohol, which potentiate these preparations (Asava-Arishta), pharmaceutically and therapeutically. Commonly, medicinal and commercial components of these formulations are prompting many researchers to contribute in manufacturing, quality control, safety, and efficacy of these formulations. To cope up with this, literature related to Asava-Arishta has been surveyed from the Vedic period to recent publications of Government of India, ie, Ayurvedic Formulary of India, and presented briefly here. In this review paper, we have discussed pioneering facts such as nature and amount of carbohydrate, type of containers, optimum temperature, variety and relevance of initiator of fermentation, manufacturing, regulatory rules, and business aspects of Asava-Arishta. After going through this basic information, any academician or researcher may show a way to further strengthen this dosage form.

Keywords: Arishta; Asava; Sandhana kalpana; ethyl alcohol; fermentation; quality control.

PubMed Disclaimer

References

    1. Natrajan S. Gurgaon, Haryana: Ranbaxy Science Foundation; 2006. Plant extracts as active botanical ingredients. Herbal Drugs – Perspective in the new Millennium; p. 45.
    1. Acarya Vaidya Jadava JI Trikamji. Charak Samhita with commentary of Cakrapanidatta. 07. 04. New Delhi: Rashtriya Sanskrita Sansthan (Deemed to be University); 2002. p. 31. Sutra Sthana verse. 1941.
    1. Acarya Vaidya Jadava JI Trikamji. Sushruta Samhita with commentary of Dalhana. 7th ed. 194. Vol. 45. Varanasi: Chaukhambha Orientalia; 2002. p. 211. Sutra Sthana.
    1. Sastry Pandit Parasuram. Madhyam Khanda. 5th ed. 01. Vol. 10. Varanasi: Chaukhambha Orientalia; 2002. Sharangadhar Samhita with commentary of Adhmalla's Dipika and Kashiram's Gudartha-Dipika; p. 232.
    1. Muralidhar R, Chaudhary A, Ravishankar B, Dey S, Prajapati P K. A comparative Pharmaceutico-pharmacoclinical study of different samples of Shirisharishta and its shwashara effect. AYU. 2004;7:45–9.