Extrachromosomal psi+ determinant suppresses nonsense mutations in yeast
- PMID: 225301
- PMCID: PMC218059
- DOI: 10.1128/jb.139.3.1068-1071.1979
Extrachromosomal psi+ determinant suppresses nonsense mutations in yeast
Abstract
The extrachromosomal psi+ determinant in the yeast Saccharomyces cerevisiae enhanced the expression of Mendelian UAA suppressors by 6- to 10-fold. The psi+ determinant by itself is a weak UAA suppressor that caused the production of approximately 1% of the normal level of iso-1-cytochrome c in a strain containing the UAA mutation cycl-72.
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