Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Aug;21(8):1459-70.
doi: 10.1007/s00586-012-2297-9. Epub 2012 Apr 25.

Lack of uniform diagnostic criteria for cervical radiculopathy in conservative intervention studies: a systematic review

Affiliations

Lack of uniform diagnostic criteria for cervical radiculopathy in conservative intervention studies: a systematic review

Erik J Thoomes et al. Eur Spine J. 2012 Aug.

Abstract

Purpose: Cervical radiculopathy (CR) is a common diagnosis. It is unclear if intervention studies use uniform definitions and criteria for patient selection. Our objective was to assess the uniformity of diagnostic criteria and definitions used in intervention studies to select patients with CR.

Methods: We electronically searched the Cochrane Controlled Trials Register, MEDLINE, EMBASE and CINAHL. Studies were included when evaluating conservative interventions in randomised clinical trials (RCTs) in patients with CR. Selection criteria and definitions for patients with CR were extracted and evaluated on their uniformity.

Results: Thirteen RCTs were included. Pain was used as an inclusion criterion in 11 studies. Inclusion based on the duration and location of pain varied between studies. Five studies used sensory symptoms in the arm as inclusion criterion. Four studies used cervical range of motion and motor disturbances as inclusion criteria, while reflex changes were used in two studies. Three studies included patients with a positive Spurling's test and two studies used it within a cluster of provocation tests.

Conclusions: Criteria used to select patients with CR vary widely between different intervention studies. Selection criteria and test methods used are poorly described. There is consensus on the presence of pain, but not on the exact location of pain.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
PRISMA flow diagram

References

    1. Kuijper B, Tans JThJ, Schimscheimer RJ, van der Kallen BFW, Beelen A, Nollet F, de Visser M. Degenerative cervical radiculopathy: diagnosis and conservative treatment. A review. Eur J Neurol. 2009;16:15–20. doi: 10.1111/j.1468-1331.2008.02365.x. - DOI - PubMed
    1. Radhakrishnan K, Litchy WJ, O’fallon WM, Kurland LT. Epidemiology of cervical radiculopathy a population-based study from Rochester, Minnesota. Brain. 1994;117:325–335. doi: 10.1093/brain/117.2.325. - DOI - PubMed
    1. Salemi G, Savettieri G, Meneghini F, Di Benedetto ME, Ragonese P, Morgante L, Reggio A, Patti F, Grigoletto F, Di Perri R. Prevalence of cervical spondylotic radiculopathy: a door-to-door survey in a Sicilian municipality. Acta Neurol Scand. 1996;93:184–188. doi: 10.1111/j.1600-0404.1996.tb00196.x. - DOI - PubMed
    1. Carette S, Fehlings MG. Clinical practice. Cervical radiculopathy. N Engl J Med. 2005;353(4):392–399. doi: 10.1056/NEJMcp043887. - DOI - PubMed
    1. Nobuhiro T, Yoshinori F, Howard S, Yoshikazu I, Mineo Y. The anatomic relation among the nerve roots, intervertebral foramina, and intervertebral discs of the cervical spine. Spine. 2000;3:286–291. - PubMed

Publication types

LinkOut - more resources