[Improved prognosis in light chain nephropathy due to multiple myeloma]

Abstract

A 64 year-old woman with acute renal failure and cast nephropathy due to excessive production of lambda free light chains received chemotherapy (using bortezomib and dexamethason) and haemodialysis with a high cut off-filter. The concentration of free light chains was markedly reduced after a fortnight. Nine months after admission, the patient's kidney function had improved and dialysis was stopped. Three months later, she got an autologous stem cell transplantation. One year later, estimated glomerular filtration rate was 25 ml/min, and the production of free light chains was under control.