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. 2012:2012:216380.
doi: 10.1100/2012/216380. Epub 2012 Mar 12.

Two new reference materials based on tobacco leaves: certification for over a dozen of toxic and essential elements

Zbigniew Samczyński  1 , Rajmund S Dybczyński, Halina Polkowska-Motrenko, Ewelina Chajduk, Marta Pyszynska, Bożena Danko, Elżbieta Czerska, Krzysztof Kulisa, Katarzyna Doner, Paweł Kalbarczyk
Affiliations

Two new reference materials based on tobacco leaves: certification for over a dozen of toxic and essential elements

Zbigniew Samczyński et al. ScientificWorldJournal. 2012.

Abstract

The preparation, certification, and characterization of two new biological certified reference materials for inorganic trace analysis have been presented. They are based on two different varieties of tobacco leaves, namely, Oriental Basma Tobacco Leaves (INCT-OBTL-5), grown in Greece, and Polish Virginia Tobacco Leaves (INCT-PVTL-6), grown in Poland. Certification of the materials was based on the statistical evaluation of results obtained in a worldwide interlaboratory comparison, in which 87 laboratories from 18 countries participated, providing 2568 laboratory averages on nearly 80 elements. It was possible to establish the certified values of concentration for many elements in the new materials, that is, 37 in INCT-OBTL-5 and 36 in INCT-PVTL-6, including several toxic ones like As, Cd, Hg, Pb, and so forth. The share and the role of instrumental analytical techniques used in the process of certification of the new CRMs are discussed.

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Figures

Figure 1
Figure 1
General strategy of production and certification of the new reference materials.
Figure 2
Figure 2
Particle size distribution of the candidate reference materials: Oriental Basma Tobacco Leaves (INCT-OBTL-5) and Polish Virginia Tobacco Leaves (INCT-PVTL-6).
Figure 3
Figure 3
Water desorption curves for INCT-OBTL-5 and INCT-PVTL-6 at 75 and 85°C.
Figure 4
Figure 4
Changes of the overall mean and its standard deviation for As in INCT-PVTL-6 observed while executing the outlier's rejection procedure.
Figure 5
Figure 5
Z-shaped plots for Co in INCT-PVTL-6 while processing the original (a) and alternative databases (b). Laboratories qualified as outliers are marked with filled symbols; a solid horizontal line represents the overall mean and dashed lines confidence limits.
Figure 6
Figure 6
Comparison of the overall means and their confidence intervals for Cd and As in INCT-PVTL-6 obtained from the original and alterative databases with the result obtained by the definitive method and the ranges of laboratory averages.
Figure 7
Figure 7
Comparison of the finally calculated overall mean (from the alternative database) for Zn and Cr in INCT-OBTL-5 and the means obtained for particular analytical techniques, together with the respective confidence intervals.
Figure 8
Figure 8
The share of analytical techniques in the certification process of INCT-OBTL-5 and INCT-PVTL-6.
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