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. 2012 Apr 26:4:14.
doi: 10.1186/1758-3284-4-14.

Delay in pathological tissue processing time vs. mortality in oral cancer: short communication

Waseem Jerjes  1 , Tahwinder Upile, Hani Radhi, Aviva Petrie, Aidan Adams, Jacqueline Callear, Panagiotis Kafas, Colin Hopper
Affiliations

Delay in pathological tissue processing time vs. mortality in oral cancer: short communication

Waseem Jerjes et al. Head Neck Oncol. .

Expression of concern in

  • Comment: Head and Neck Oncology.
    BioMed Central. BioMed Central. BMC Med. 2014 Feb 5;12:24. doi: 10.1186/1741-7015-12-24. BMC Med. 2014. PMID: 24499430 Free PMC article. Review.

Abstract

Several factors have been identified to affect morbidity and mortality in oral cancer patients. The time taken to process a resected cancer specimen in a patient presenting with primary or recurrent disease can be of interest as delay can affect earlier interventions post-surgery. We looked at this variable in a group of 168 consecutive oral cancer patients and assessed its relationship to mortality from the disease at 3 and 5 years. It is expected that delay in pathological processing time of surgical specimens acquired from patients with recurrent disease may increase or contribute to the increased rate of mortality. Further high evidence-based studies are required to confirm this.

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Figures

Figure 1
Figure 1
Pathological processing time of the resected specimens. “Duration 1” refers to the time (in days) taken to process and report on the resected tissue of the primary tumour. While “Duration 2” refers to the time (in days) taken to process and report on the resected tissue of the recurrent disease.
Figure 2
Figure 2
Duration 1 versus survival at 3 years. “Duration 1” refers to the time (in days) taken to process and report on the resected tissue of the primary tumour.
Figure 3
Figure 3
Duration 1 versus survival at 5 years. “Duration 1” refers to the time (in days) taken to process and report on the resected tissue of the primary tumour.
Figure 4
Figure 4
Duration 2 versus survival at 3 years. “Duration 2” refers to the time (in days) taken to process and report on the resected tissue of the recurrent disease.
Figure 5
Figure 5
Duration 2 versus survival at 5 years. “Duration 2” refers to the time (in days) taken to process and report on the resected tissue of the recurrent disease.
See this image and copyright information in PMC

References

    1. Jerjes W, Upile T, Petrie A, Riskalla A, Hamdoon Z, Vourvachis M, Karavidas K, Jay A, Sandison A, Thomas GJ, Kalavrezos N, Hopper C. Clinicopathological parameters, recurrence, locoregional and distant metastasis in 115 T1-T2 oral squamous cell carcinoma patients. Head Neck Oncol. 2010;2:9. doi: 10.1186/1758-3284-2-9. - DOI - PMC - PubMed
    1. Bagan JV, Scully C. Recent advances in Oral Oncology 2007: epidemiology, aetiopathogenesis, diagnosis and prognostication. Oral Oncol. 2008;44(2):103–108. doi: 10.1016/j.oraloncology.2008.01.008. - DOI - PubMed
    1. Garzino-Demo P, Dell'Acqua A, Dalmasso P, Fasolis M, La Terra Maggiore GM, Ramieri G, Berrone S, Rampino M, Schena M. Clinicopathological parameters and outcome of 245 patients operated for oral squamous cell carcinoma. J Craniomaxillofac Surg. 2006;34(6):344–350. doi: 10.1016/j.jcms.2006.04.004. - DOI - PubMed