Comment
doi: 10.1016/j.cell.2012.04.003.
Dialing down SUN1 for laminopathies
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- PMID: 22541423
- DOI: 10.1016/j.cell.2012.04.003
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Comment
Dialing down SUN1 for laminopathies
Cell.
.
Free article
Abstract
Laminopathies, caused by mutations in A-type nuclear lamins, encompass a range of diseases, including forms of progeria and muscular dystrophy. In this issue, Chen et al. provide evidence that elevated expression of the nuclear inner membrane protein SUN1 drives pathology in multiple laminopathies.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies.Cell. 2012 Apr 27;149(3):565-77. doi: 10.1016/j.cell.2012.01.059. Cell. 2012. PMID: 22541428 Free PMC article.
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