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Comment
. 2012 Apr 26;74(2):211-3.
doi: 10.1016/j.neuron.2012.04.003.

The CAP-Gly of p150: one domain, two diseases, and a function at the end

Michelle A Cronin  1 , Thomas L Schwarz
Affiliations
Comment

The CAP-Gly of p150: one domain, two diseases, and a function at the end

Michelle A Cronin et al. Neuron. .

Abstract

In this issue of Neuron, work from Moughamian and Holzbaur (2012) and Lloyd et al. (2012) reveals a role for p150 in initiation of retrograde transport at synaptic terminals. These studies also suggest how mutations of p150's CAP-Gly domain lead to both Perry syndrome and HMN7B disease.

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Figures

Figure 1
Figure 1
The CAP-Gly domain of p150 is required for initiation of dynein loading at (+) ends
See this image and copyright information in PMC

Comment on

References

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