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. 2012 Apr 26;74(2):214-7.
doi: 10.1016/j.neuron.2012.04.005.

Synapses let loose for a change: inhibitory synapse pruning throughout experience-dependent cortical plasticity

Frédéric Gambino  1 , Anthony Holtmaat
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Synapses let loose for a change: inhibitory synapse pruning throughout experience-dependent cortical plasticity

Frédéric Gambino et al. Neuron. .
Free article

Abstract

In this issue of Neuron, Chen et al. (2012) and van Versendaal et al. (2012) used fluorescently tagged gephyrin to track inhibitory synapses in the mouse visual cortex in vivo. Their studies show that visual experience-dependent plasticity is associated with clustered and location-specific pruning of inhibitory synapses.

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