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Comparative Study
. 1990 Dec;172(12):6973-80.
doi: 10.1128/jb.172.12.6973-6980.1990.

Recombination at ColE1 cer requires the Escherichia coli xerC gene product, a member of the lambda integrase family of site-specific recombinases

S D Colloms  1 , P Sykora, G Szatmari, D J Sherratt
Affiliations
Comparative Study

Recombination at ColE1 cer requires the Escherichia coli xerC gene product, a member of the lambda integrase family of site-specific recombinases

S D Colloms et al. J Bacteriol. 1990 Dec.

Abstract

Site-specific recombination at the plasmid ColE1 cer site requires the Escherichia coli chromosomal gene xerC. The xerC gene has been localized to the 85-min region of the E. coli chromosome, between cya and uvrD. The nucleotide sequences of the xerC gene and flanking regions have been determined. The xerC gene encodes a protein with a calculated molecular mass of 33.8 kDa. This protein has substantial sequence similarity to the lambda integrase family of site-specific recombinases and is probably the cer recombinase. The xerC gene is expressed as part of a multicistronic unit that includes the dapF gene and two other open reading frames.

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References

    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. EMBO J. 1989 May;8(5):1623-7 - PubMed
    1. Proc Natl Acad Sci U S A. 1972 Aug;69(8):2110-4 - PubMed
    1. Bacteriol Rev. 1972 Dec;36(4):525-57 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7 - PubMed

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