Isolation and characterization of Bacillus stearothermophilus 30S and 50S ribosomal protein mutations
- PMID: 2254291
- PMCID: PMC210864
- DOI: 10.1128/jb.172.12.7306-7309.1990
Isolation and characterization of Bacillus stearothermophilus 30S and 50S ribosomal protein mutations
Abstract
Bacillus stearothermophilus mutations which confer resistance to or dependence on a variety of ribosome-targeted antibiotics have been isolated. Many of these mutations produce ribosomal proteins with altered mobilities in a two-dimensional gel electrophoresis system. This collection of altered thermophilic ribosomal proteins will be useful in examining ribosomal structure and function.
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