Neurodegenerative disease: The stress of misfolding

Comment

Darran Yates. Nat Rev Drug Discov. 2012.

. 2012 Apr 30;11(5):352-3.

doi: 10.1038/nrd3731.

No abstract available

Comment on

Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo.
Colla E, Jensen PH, Pletnikova O, Troncoso JC, Glabe C, Lee MK. Colla E, et al. J Neurosci. 2012 Mar 7;32(10):3301-5. doi: 10.1523/JNEUROSCI.5368-11.2012. J Neurosci. 2012. PMID: 22399752 Free PMC article.
Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo.
Colla E, Coune P, Liu Y, Pletnikova O, Troncoso JC, Iwatsubo T, Schneider BL, Lee MK. Colla E, et al. J Neurosci. 2012 Mar 7;32(10):3306-20. doi: 10.1523/JNEUROSCI.5367-11.2012. J Neurosci. 2012. PMID: 22399753 Free PMC article.