Comment
doi: 10.1038/ki.2012.30.
Renal vitamin D receptor expression and vitamin D renoprotection
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- PMID: 22543902
- DOI: 10.1038/ki.2012.30
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Comment
Renal vitamin D receptor expression and vitamin D renoprotection
Kidney Int.
2012 May.
Free article
Abstract
Therapy to enhance the renoprotective actions of vitamin D receptor (VDR) activation should safely overcome the distinct VDR content along the nephron to effectively control renal calcium reabsorption, control renal klotho levels for the phosphaturic actions of FGF23, and inhibit proteinuria and the activation of the renin-angiotensin system.
Comment on
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Identification of the vitamin D receptor in various cells of the mouse kidney.Kidney Int. 2012 May;81(10):993-1001. doi: 10.1038/ki.2011.463. Epub 2012 Jan 25. Kidney Int. 2012. PMID: 22278022 Free PMC article.
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