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Review
. 2012 Apr 30:4:16.
doi: 10.1186/1758-3284-4-16.

Photodynamic therapy in the management of potentially malignant and malignant oral disorders

Waseem Jerjes  1 , Zaid Hamdoon, Colin Hopper
Affiliations
Review

Photodynamic therapy in the management of potentially malignant and malignant oral disorders

Waseem Jerjes et al. Head Neck Oncol. .

Expression of concern in

  • Comment: Head and Neck Oncology.
    BioMed Central. BioMed Central. BMC Med. 2014 Feb 5;12:24. doi: 10.1186/1741-7015-12-24. BMC Med. 2014. PMID: 24499430 Free PMC article. Review.

Abstract

Photodynamic therapy (PDT) is a minimally-invasive surgical tool successfully targeting premalignant and malignant disorders in the head and neck, gastrointestinal tract, lungs and skin with greatly reduced morbidity and disfigurement. The technique is simple, can commonly be carried out in outpatient clinics, and is highly acceptable to patients. The role of photodynamic therapy in the management of oral potentially malignant disorders and early oral cancer is being discussed.

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Figures

Figure 1
Figure 1
Clinical images showing response of moderate oral dysplasia to photodynamic therapy. Adapted with permission from: Jerjes W, Upile T, Hamdoon Z, Mosse CA, Akram S, Hopper. Photodynamic therapy outcome for oral dysplasia. Lasers Surg Med. 2011 Mar;43(3):192–9.
Figure 2
Figure 2
Clinical image of SCC of the oral cavity and ventral tongue responded favourably to photodynamic therapy. Adapted with permission from: Jerjes W, Upile T, Hamdoon Z, Alexander Mosse C, Morcos M, Hopper C. Photodynamic therapy outcome for T1/T2 N0 oral squamous cell carcinoma. Lasers Surg Med. 2011 Aug;43(6):463–9.
See this image and copyright information in PMC

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