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. 2012 May 1;3(3):329-38.
doi: 10.4161/viru.20142. Epub 2012 May 1.

Mouse models for the study of fungal pneumonia: a collection of detailed experimental protocols for the study of Coccidioides, Cryptococcus, Fusarium, Histoplasma and combined infection due to Aspergillus-Rhizopus

Maged Muhammed  1 , Marta Feldmesser, Lisa F Shubitz, Michail S Lionakis, Anita Sil, Yan Wang, Justin Glavis-Bloom, Russell E Lewis, John N Galgiani, Arturo Casadevall, Dimitrios P Kontoyiannis, Eleftherios Mylonakis
Affiliations

Mouse models for the study of fungal pneumonia: a collection of detailed experimental protocols for the study of Coccidioides, Cryptococcus, Fusarium, Histoplasma and combined infection due to Aspergillus-Rhizopus

Maged Muhammed et al. Virulence. .

Abstract

Mouse models have facilitated the study of fungal pneumonia. In this report, we present the working protocols of groups that are working on the following pathogens: Aspergillus, Coccidioides, Cryptococcus, Fusarium, Histoplasma and Rhizopus. We describe the experimental procedures and the detailed methods that have been followed in the experienced laboratories to study pulmonary fungal infection; we also discuss the anticipated results and technical notes, and provide the practical advices that will help the users of these models.

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