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Case Reports
. 2012 Aug;31(8):873-6.
doi: 10.1097/INF.0b013e31825ba6cf.

Leukoreduction in patients with severe pertussis with hyperleukocytosis

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Case Reports

Leukoreduction in patients with severe pertussis with hyperleukocytosis

Gonzalo Oñoro et al. Pediatr Infect Dis J. 2012 Aug.

Abstract

When pertussis is associated with hyperleukocytosis, mortality approaches to 80%. Immature leukocytes have been identified in pulmonary arterioles, small arteries and venules. Techniques aimed at reducing leukocyte mass might improve the prognosis of these patients. We report our experience with 3 patients in whom a leukoreduction was performed in the context of severe pertussis and hyperleukocytosis.

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