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Review
. 2012 May 1;4(5):a011163.
doi: 10.1101/cshperspect.a011163.

Wnt signaling

Affiliations
Review

Wnt signaling

Roel Nusse. Cold Spring Harb Perspect Biol. .

Abstract

Wnt proteins bind to Frizzled family members on the surface of the cell to regulate developmental processes (e.g., cell fate and morphogenesis).

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Figures

Figure 1.
Figure 1.
Canonical Wnt signaling.
Figure 2.
Figure 2.
Non-canonical Wnt signaling pathways.

References

    1. Cadigan KM, Peifer M 2009. Wnt signaling from development to disease: Insights from model systems. Cold Spring Harb Perspect Biol 1: a002881. - PMC - PubMed
    1. Grigoryan T, Wend P, Klaus A, Birchmeier W 2008. Deciphering the function of canonical Wnt signals in development and disease: Conditional loss- and gain-of-function mutations of β-catenin in mice. Genes Dev 22: 2308–2341 - PMC - PubMed
    1. Hemmings B 2012. P13K/AKT pathway. Cold Spring Harb Perspect Biol 10.1101/cshperspect.011189 - DOI - PMC - PubMed
    1. Lapalante M, Sabatini D 2012. mTOR signaling. Cold Spring Harb Perspect Biol 10.1101/cshperspect.011593 - DOI - PMC - PubMed
    1. Neel B, Muthuswarmy S 2012. Signaling in development 2—cell differentiation. Cold Spring Harb Perspect Biol 10.1101/cshperspect.005884 - DOI

MeSH terms

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