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Review
. 2012 May 1;4(5):a013441.
doi: 10.1101/cshperspect.a013441.

On stem cells in the human breast

Mark A LaBarge  1
Affiliations
Review

On stem cells in the human breast

Mark A LaBarge. Cold Spring Harb Perspect Biol. .

Abstract

In the human breast, stem cells give rise to myoepithelial and luminal epithelial cells that are needed during monthly estrous cycles and lactation. The mechanisms that govern mammary stem cells are hotly debated.

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Comment on

  • Stem cells in the human breast.
    Petersen OW, Polyak K. Petersen OW, et al. Cold Spring Harb Perspect Biol. 2010 May;2(5):a003160. doi: 10.1101/cshperspect.a003160. Cold Spring Harb Perspect Biol. 2010. PMID: 20452965 Free PMC article. Review.

References

    1. Blau HM, Brazelton TR, Weimann JM 2001. The evolving concept of a stem cell: Entity or function? Cell 105: 829–841 - PubMed
    1. Booth BW, Mack DL, Androutsellis-Theotokis A, McKay RD, Boulanger CA, Smith GH 2008. The mammary microenvironment alters the differentiation repertoire of neural stem cells. Proc Natl Acad Sci 105: 14891–14896 - PMC - PubMed
    1. Boulanger CA, Mack DL, Booth BW, Smith GH 2007. Interaction with the mammary microenvironment redirects spermatogenic cell fate in vivo. Proc Natl Acad Sci 104: 871–876 - PMC - PubMed
    1. Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M, et al. 2010. Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. Cell Stem Cell 6: 251–264 - PMC - PubMed
    1. Flaim CJ, Chien S, Bhatia SN 2005. An extracellular matrix microarray for probing cellular differentiation. Nat Methods 2: 119–125 - PubMed