Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2012 May 2:7:40.
doi: 10.1186/1749-8090-7-40.

Sternal reconstruction for unusual chondrosarcoma: innovative technique

Affiliations
Case Reports

Sternal reconstruction for unusual chondrosarcoma: innovative technique

Mario Nosotti et al. J Cardiothorac Surg. .

Abstract

The authors report a clinical case of a primary sternal chondrosarcoma, presented as a mass in the anterior mediastinum. The patient was treated with subtotal sternectomy and sternal transplantation followed by radiotherapy. Twelve months after surgery, the patient is in good clinical condition, without any sign of tumor relapse and with normal respiratory mechanics. Primary malignant tumors of the sternum are uncommon and a presentation mimicking thymoma is rare and unreported. The stermal replacement with a cryopreserved allograft sternum is an innovative technique that overcomes the problems related to the prosthetic biocompatibility or to the bone autograft.

PubMed Disclaimer

Figures

Figure 1
Figure 1
CT images show the mass into the anterior mediastinum. On the right it is possible to observe the calcified connection between the mass and the sternum; no cortical erosion is present.
Figure 2
Figure 2
CT scan reconstruction 2 months after surgery. The transplanted sternum appears well integrated with the rib cage.

References

    1. Somers J, Faber LP. Chondroma and chondrosarcoma. Semin Thorac Cardiovasc Surg. 1999;11:270–277. - PubMed
    1. Chapelier AR, Missana MC, Couturaud B. et al.Sternal resection and reconstruction for primary malignant tumors. Ann Thorac Surg. 2004;77:1001–1006. doi: 10.1016/j.athoracsur.2003.08.053. - DOI - PubMed
    1. Ashford RU, Stanton J, Khan F, Pringle JA, Cannon SR, Briggs TW. Surgical treatment of chondrosarcoma of the sternum. Sarcoma. 2001;5:209–213. doi: 10.1080/13577140120099209. - DOI - PMC - PubMed
    1. Granero-Molto F, Weis JA, Longobardi L, Spagnoli A. Role of mesenchymal stem cells in regenerative medicine: application to bone and cartilage repair. Expert Opin Biol Ther. 2008;8:255–268. doi: 10.1517/14712598.8.3.255. - DOI - PubMed
    1. Marulli G, Hamad AM, Cogliati E, Breda C, Zuin A, Rea F. Allograft sternochondral replacement after resection of large sternal chondrosarcoma. J Thorac Cardiovasc Surg. 2010;139:e69–e70. doi: 10.1016/j.jtcvs.2009.01.007. - DOI - PubMed

Publication types

Substances