Directed therapies in lung cancer: new hope?
- PMID: 22551924
- DOI: 10.1016/j.arbres.2012.03.007
Directed therapies in lung cancer: new hope?
Abstract
Lung cancer (LC) is a serious health problem due to its high incidence and mortality. Surgery is the most effective therapeutic strategy in this type of tumor, but in recent years new drugs are being investigated that target specific components of the tumor cells, improving survival in patients with advanced disease and relapse. We present a review of individualized treatments in LC, particularly therapies that inhibit epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF) and anaplastic lymphoma kinase (ALK).
Copyright © 2011 SEPAR. Published by Elsevier España, S.L. All rights reserved.
Similar articles
-
The emerging role of vascular endothelial growth factor receptor tyrosine kinase inhibitors.Semin Oncol. 2005 Dec;32(6 Suppl 10):S23-9. doi: 10.1053/j.seminoncol.2005.10.005. Semin Oncol. 2005. PMID: 16459176 Review.
-
The role of anti-epidermal growth factor receptor and anti-vascular endothelial growth factor therapies in the treatment of non-small-cell lung cancer.Clin Lung Cancer. 2010 Mar 1;11(2):82-90. doi: 10.3816/CLC.2010.n.011. Clin Lung Cancer. 2010. PMID: 20199973 Review.
-
[Personalized treatment in non-small cell lung cancer].Rev Invest Clin. 2012 Jul-Aug;64(4):377-86. Rev Invest Clin. 2012. PMID: 23227588 Review. Spanish. No abstract available.
-
Targeted therapies in the treatment of advanced non-small-cell lung cancer: update.Klin Onkol. 2009;22(4):131-8. Klin Onkol. 2009. PMID: 19731875 Review.
-
Update on systemic therapy of advanced non-small-cell lung cancer.Expert Rev Anticancer Ther. 2014 Oct;14(10):1189-203. doi: 10.1586/14737140.2014.940327. Epub 2014 Aug 7. Expert Rev Anticancer Ther. 2014. PMID: 25098682 Review.
Cited by
-
Novel aminochromone derivative inhibits tumor growth on xenograft model of lung cancer in mice.J Adv Pharm Technol Res. 2018 Oct-Dec;9(4):130-134. doi: 10.4103/japtr.JAPTR_313_18. J Adv Pharm Technol Res. 2018. PMID: 30637230 Free PMC article.
-
Risk Factors for Short-Term Lung Cancer Survival.J Clin Med. 2021 Feb 1;10(3):519. doi: 10.3390/jcm10030519. J Clin Med. 2021. PMID: 33535673 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Research Materials
Miscellaneous