Size of infectious DNA from human and murine cytomegaloviruses
- PMID: 225527
- PMCID: PMC353339
- DOI: 10.1128/JVI.30.1.414-416.1979
Size of infectious DNA from human and murine cytomegaloviruses
Abstract
Viral DNA was isolated from human and murine cytomegalovirus by equilibrium centrifugation in cesium chloride gradients. The size of the DNA was measured relative to T4 DNA by velocity sedimentation in neutral glycerol gradients, and fractions were assayed for infectious DNA. Infectious murine cytomegalovirus DNA sedimented as a single peak with an estimated molecular weight of 136 X 10(6). Infectious human cytomegalovirus DNA was detected in two peaks with molecular weights of 130 X 10(6) and 150 X 10(6).
Similar articles
-
Human cytomegalovirus DNA. I. Molecular weight and infectivity.J Virol. 1978 Jun;26(3):813-6. doi: 10.1128/JVI.26.3.813-816.1978. J Virol. 1978. PMID: 209219 Free PMC article.
-
Equine cytomegalovirus: cultural characteristics and properties of viral DNA.Virology. 1981 Feb;109(1):106-19. doi: 10.1016/0042-6822(81)90475-x. Virology. 1981. PMID: 6258303 No abstract available.
-
Propagation and purification of high-titer human cytomegalovirus.Appl Microbiol. 1971 Nov;22(5):914-8. doi: 10.1128/am.22.5.914-918.1971. Appl Microbiol. 1971. PMID: 4332045 Free PMC article.
-
Human cytomegalovirus. I. Purification and characterization of viral DNA.J Virol. 1973 Dec;12(6):1473-81. doi: 10.1128/JVI.12.6.1473-1481.1973. J Virol. 1973. PMID: 4128379 Free PMC article.
-
Cytomegaloviruses of man and animals.Prog Med Virol. 1973;15:92-125. Prog Med Virol. 1973. PMID: 4348878 Review. No abstract available.
Cited by
-
Structure of the heterogeneous L-S junction region of human cytomegalovirus strain AD169 DNA.J Virol. 1984 Nov;52(2):541-8. doi: 10.1128/JVI.52.2.541-548.1984. J Virol. 1984. PMID: 6092675 Free PMC article.
-
Varicella zoster virus DNA exists as two isomers.Proc Natl Acad Sci U S A. 1982 Jan;79(1):156-60. doi: 10.1073/pnas.79.1.156. Proc Natl Acad Sci U S A. 1982. PMID: 6275385 Free PMC article.
-
Terminal structure and heterogeneity in human cytomegalovirus strain AD169.J Virol. 1986 Sep;59(3):591-604. doi: 10.1128/JVI.59.3.591-604.1986. J Virol. 1986. PMID: 3016322 Free PMC article.
-
Five families of diverse DNA viruses comprehensively restructure the nucleus.PLoS Biol. 2023 Nov 6;21(11):e3002347. doi: 10.1371/journal.pbio.3002347. eCollection 2023 Nov. PLoS Biol. 2023. PMID: 37930945 Free PMC article.
-
Structure of the transforming region of human cytomegalovirus AD169.J Virol. 1984 Jan;49(1):109-15. doi: 10.1128/JVI.49.1.109-115.1984. J Virol. 1984. PMID: 6317885 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources