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. 2011;4(1):73-7.
doi: 10.3980/j.issn.2222-3959.2011.01.17. Epub 2011 Feb 18.

Laser treatment in 341 patients with exudative age-related macular degeneration

Leyla Atmaca  1 , Aysun Idil, Pelin Atmaca-Sönmez
Affiliations

Laser treatment in 341 patients with exudative age-related macular degeneration

Leyla Atmaca et al. Int J Ophthalmol. 2011.

Abstract

Aim: To document the prognosis of laser treatment in patients with exudative age-related macular degeneration (AMD).

Methods: Efficacy of the intervention was evaluated using a before-after method.

Results: A total of 392 eyes of 341 patients with exudative AMD were examined. 77.6% had choroideal neovascularisation (CNV). Before the use of indocyanine green (ICG) angiography, occult CNV was detected in only 1.8% of the eyes, but after the use of ICG angiography, this increased to 19.5% (P<0.001). Of the 349 eyes which were followed up, visual acuity had remained stable in 68.2%. There was a statistically significant relationship between the localization of lesion and visual acuity changes on pre- and post-laser treatment (P<0.001). Also there was a statistically significant relationship between the localization of lesion and recurrence (P<0.05). The recurrence was less in subfoveal lesions than that in juxtafoveal and extrafoveal lesions.

Conclusion: ICG angiography is highly important in the treatment of occult CNV.

Keywords: dye laser; exudative age-related macular degeneration; green argon laser; indocyanine green angiography; red krypton laser.

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Figures

Figure 1
Figure 1. Subfoveal CNV before and one month after laser treatment
A: Before VA: 20/400; B: After VA: 20/200
Figure 2
Figure 2. Juxtafoveal CNV with red krypton laser treatment
A: Before VA:0.4; B: Three months after laser treatment VA:0.7
Figure 3
Figure 3. Extrafoveal CNV after red krypton laser
A: Immediately VA:0.7; B: One month after laser treatment VA:0.7
Figure 4
Figure 4. Hyperfluorescent
A:PED(FA); B:Late-phase ICG
Figure 5
Figure 5. Juxtafoveal CNV with laser treatment
A: Before VA:0.5; B: 15 days after first treatment VA:0.5; C: 18 days after second treatment VA:0.3; D: 20 days after third treatment VA:0.3
See this image and copyright information in PMC

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