Laboratory diagnosis of infectious endophthalmitis

doi:10.3980/j.issn.2222-3959.2011.01.23

. 2011;4(1):100-2.

doi: 10.3980/j.issn.2222-3959.2011.01.23. Epub 2011 Feb 18.

Laboratory diagnosis of infectious endophthalmitis

Wen-Jiang Ma¹, Hong Zhang, Shao-Zhen Zhao

Affiliations

PMID: 22553620
PMCID: PMC3340684
DOI: 10.3980/j.issn.2222-3959.2011.01.23

Laboratory diagnosis of infectious endophthalmitis

Wen-Jiang Ma et al. Int J Ophthalmol. 2011.

. 2011;4(1):100-2.

doi: 10.3980/j.issn.2222-3959.2011.01.23. Epub 2011 Feb 18.

Authors

Wen-Jiang Ma¹, Hong Zhang, Shao-Zhen Zhao

Affiliation

¹ Eye Centre, Tianjin Medical University, Tianjin 300070, China.

PMID: 22553620
PMCID: PMC3340684
DOI: 10.3980/j.issn.2222-3959.2011.01.23

Abstract

Aim: To analyze the lab diagnosis and etiology of infectious endophthalmitis.

Methods: The medical and microbial records of 36 patients diagnosed with infectious endophthalmitis and 8 patients diagnosed with intraocular lens (IOL)-related inflammation between Nov. 1999 and Dec. 2009 were retrospectively reviewed for lab diagnosis and etiology.

Results: The inflammatory cell counts in all aqueous humor specimens from infectious endophthalmitis patients were more than in all aqueous humor specimens from patients with IOL-related inflammation. Sixteen of the 36 aqueous humor samples (44.4%) and 11 of the 24 vitreous humor samples (45.8%) from infectious endophthalmitis patients showed positive results in smears; while 17 aqueous humor samples (47.2%) and 15 vitreous humor samples (62.5%) from infectious endophthalmitis patients showed positive results in culture.

Conclusion: The inflammatory cell count may be an important index for infectious endophthalmitis; while, smears can show etiological information earlier.

Keywords: IOL-related inflammation; infectious endophthalmitis; laboratory diagnosis.

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References

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[1] Jambulingam M, Parameswaran SK, Lysa S, Selvaraj M, Madhavan HN. A study on the incidence, microbiological analysis and investigations on the source of infection of postoperative infectious endophthalmitis in a tertiary care ophthalmic hospital: an 8-year study. Indian J Ophthalmol. 2010;58(4):297–302. - PMC - PubMed

[2] Jambulingam M, Parameswaran SK, Lysa S, Selvaraj M, Madhavan HN. A study on the incidence, microbiological analysis and investigations on the source of infection of postoperative infectious endophthalmitis in a tertiary care ophthalmic hospital: an 8-year study. Indian J Ophthalmol. 2010;58(4):297–302. - PMC - PubMed

[3] Taban M, Behrens A, Newcomb RL, Nobe MY, McDonnell PJ. Incidence of acute endophthalmitis following penetrating keratoplasty: a systematic review. Arch Ophthalmol. 2005;123(5):605–609. - PubMed

[4] Taban M, Behrens A, Newcomb RL, Nobe MY, McDonnell PJ. Incidence of acute endophthalmitis following penetrating keratoplasty: a systematic review. Arch Ophthalmol. 2005;123(5):605–609. - PubMed

[5] Rensch F, Schlichtenbrede FC, Jonas JB. Postoperative mycotic endophthalmitis. J Cataract Refract Surg. 2010;36(7):1233–1234. - PubMed

[6] Rensch F, Schlichtenbrede FC, Jonas JB. Postoperative mycotic endophthalmitis. J Cataract Refract Surg. 2010;36(7):1233–1234. - PubMed

[7] Kernt M, Kampik A. Endophthalmitis: Pathogenesis, clinical presentation, anagement, and perspectives. Clin Ophthalmol. 2010;24(4):121–135. - PMC - PubMed

[8] Kernt M, Kampik A. Endophthalmitis: Pathogenesis, clinical presentation, anagement, and perspectives. Clin Ophthalmol. 2010;24(4):121–135. - PMC - PubMed

[9] Collee JG, Miles RS, Watt B. Tests for identification of bacteria. Collee JG, Fraser AG, Marmion BP, Simmons A, editors. Mackie and McCartney Practical Medical Microbiology. 1996;(14):131–150. In.

[10] Collee JG, Miles RS, Watt B. Tests for identification of bacteria. Collee JG, Fraser AG, Marmion BP, Simmons A, editors. Mackie and McCartney Practical Medical Microbiology. 1996;(14):131–150. In.

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Laboratory diagnosis of infectious endophthalmitis

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