Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2011;4(4):439-42.
doi: 10.3980/j.issn.2222-3959.2011.04.22. Epub 2011 Aug 18.

Bilateral scleromalacia perforans and peripheral corneal thinning in Wegener's granulomatosis

S C Reddy  1 , I Tajunisah, T Rohana
Affiliations
Case Reports

Bilateral scleromalacia perforans and peripheral corneal thinning in Wegener's granulomatosis

S C Reddy et al. Int J Ophthalmol. 2011.

Abstract

A rare case of bilateral scleromalacia perforans, bilateral peripheral corneal thinning (contact lens cornea) and unilateral orbital inflammatory disease in a 50 year old female patient with an indolent form Wegener's granulomatosis(WG) involving lungs and sinuses is reported. The patient survived for 12 years after the initial diagnosis of systemic disease. There was perforation of left globe following trauma and no perforation of the right globe till the last follow up of the patient.

Keywords: Wegener's granulomatosis; peripheral thinning of cornea; proptosis; scleromalacia perforans.

PubMed Disclaimer

Figures

Figure 1
Figure 1. Right eye showing scleral thinning in upper nasal quadrant with visible uveal tissue (thick arrow) and peripheral corneal thinning in upper and lower nasal quadrants (thin arrow)
Figure 2
Figure 2. Left eye showing scleral thinning in the upper nasal quadrant with visible uveal tissue(thick arrow) and peripheral corneal thinning in the upper and lower part of limbus(thin arrow)
Figure 3
Figure 3. MRI showing infiltration of left maxillary, ethmoidal, frontal sinuses and left orbit (arrow marks)
Figure 4
Figure 4. CT scan showing proptosis, retrobulbar infiltration (arrow) and vitreous haemorrhage (arrow) in the left eye
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Pakrou N, Selva D, Leibovitch I. Wegener's granulomatosis: Ophthlmic manifeatations and management. Semin Arthritis Rheum. 2006;35(5):284–292. - PubMed
    1. Foster CS, Yang J. Wegner's granulomatosis. In: Albert DM, Jakobiec FA, editors. Principles and practice of ophthalmology. 2nd ed. Vol. 5. Vol. 2000. Philadelphia: WB saunders; pp. 4578–4588. In:
    1. Harman LE, Margo CE. Wegner's granulomatosis. Surv Ophthalmol. 1998;42(5):458–480. - PubMed
    1. Sadiq SA, Jennings CR, Jones Ns, Downes RN. Wegener's granulomatosis: the ocular manifestations revisited. Orbit. 2000;19(4):253–261. - PubMed
    1. Bullen CL, Leisegang TJ, McDonald TJ, DeRemee RA. Ocular complications of Wegener' granulomatosis. Ophthalmology. 1983;90(3):279–290. - PubMed

Publication types

LinkOut - more resources