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Comparative Study
. 1979 Jun;30(3):720-8.
doi: 10.1128/JVI.30.3.720-728.1979.

Cell surface expression of the env gene polyprotein of dual-tropic mink cell focus-forming murine leukemia virus

N G Famulari, K Jelalian
Comparative Study

Cell surface expression of the env gene polyprotein of dual-tropic mink cell focus-forming murine leukemia virus

N G Famulari et al. J Virol. 1979 Jun.

Abstract

Differences have been observed in the kinetics of processing of the env gene polyprotein of ecotropic, xenotropic, and dual-tropic mink cell focus-forming (MCF) murine leukemia virus. In pulse-chase experiments, the env gene polyprotein of the dural-tropic MCF virus exhibits a marked increase in stability relative to that of either ecotropic or xenotropic virus. A comparison of cell surface expression of env gene products of ecotropic, xenotropic, and dual-tropic MCF murine leukemia virus has been made. Only gp70 is accessible to lactoperoxidase-catalyzed radioiodination of fibroblasts infected by ecotropic or xenotropic virus, whereas both gp70 and the env gene polyprotein are expressed on the surface of dual-tropic MCF virus-infected cells.

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References

    1. J Virol. 1978 Nov;28(2):457-65 - PubMed
    1. J Virol. 1977 Aug;23(2):430-5 - PubMed
    1. J Virol. 1977 Aug;23(2):315-22 - PubMed
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