Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Jun;30(3):936-41.
doi: 10.1128/JVI.30.3.936-941.1979.

Nucleotide sequence analysis of two simian virus 40 mutants with deletions in the region coding for the carboxyl terminus of the T antigen

H Van Heuverswyn, C Cole, P Berg, W Fiers

Nucleotide sequence analysis of two simian virus 40 mutants with deletions in the region coding for the carboxyl terminus of the T antigen

H Van Heuverswyn et al. J Virol. 1979 Jun.

Abstract

Nucleotide sequence analysis of two simian virus 40 early mutants dl1263 and dl1265, which lack a DNA segment around map positions 0.21 and 0.18, respectively (C. Cole, T. Landers, S. Goff, S. MAnteuil-Brutlag, and P. Berg, J. Virol. 24:277--294, 1977), revealed in-phase deletions of 33 nucleotide pairs for dl1263 and 39 nucleotide paris for dl1265. The 33-base-pair deletion in dl1263 does not correspond to an apparent shortening by 6,000 daltons observed for the mutant T antigen. In dl1265 the normal termination signal as well as most of the proline-rich terminal tryptic peptide has been removed, and the carboxyl terminus of the mutant T antigen is a series of three cysteine residues.

PubMed Disclaimer

References

    1. Cell. 1978 Nov;15(3):1011-20 - PubMed
    1. Nucleic Acids Res. 1978 Sep;5(9):3083-99 - PubMed
    1. Proc Natl Acad Sci U S A. 1978 May;75(5):2473-7 - PubMed
    1. Proc Natl Acad Sci U S A. 1978 May;75(5):2165-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1978 May;75(5):2160-4 - PubMed

LinkOut - more resources