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Comment
. 2012 May 4;10(5):485-7.
doi: 10.1016/j.stem.2012.04.013.

Autoimmune T cells lured to a FASL web of death by MSCs

William J Murphy  1 , Jan A Nolta
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Autoimmune T cells lured to a FASL web of death by MSCs

William J Murphy et al. Cell Stem Cell. .
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Abstract

Achieving immune tolerance through cell transplantation is a promising approach for treating autoimmune disease. In this issue of Cell Stem Cell, Akiyama et al. (2012) demonstrate that human and mouse mesenchymal stem cells can induce immune suppression by attracting and killing autoreactive T cells, which stimulates TGFb production by macrophages and generates regulatory T cells.

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