T time for point centromeres
- PMID: 22561349
- DOI: 10.1038/ncb2509
T time for point centromeres
Abstract
The diverse nature of eukaryotic centromere structure has led to a prevailing view that the kinetochore-chromatin interface is fundamentally different in distinct species. Two studies now challenge this dogma with the identification of budding yeast homologues of the vertebrate centromere DNA-binding proteins CENP-T and CENP-W.
Comment on
-
Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore.Nat Cell Biol. 2012 May 6;14(6):614-24. doi: 10.1038/ncb2495. Nat Cell Biol. 2012. PMID: 22561345 Free PMC article.
-
CENP-T proteins are conserved centromere receptors of the Ndc80 complex.Nat Cell Biol. 2012 May 6;14(6):604-13. doi: 10.1038/ncb2493. Nat Cell Biol. 2012. PMID: 22561346
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
