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Case Reports
. 2011 Oct;32(4):230-2.
doi: 10.4103/0971-5851.95148.

Fever, anemia, and splenomegaly: A rare presentation of splenic angiosarcoma

Mridula Shukla  1 , Somprakash Basu, Vijay K Shukla, Mohan Kumar
Affiliations
Case Reports

Fever, anemia, and splenomegaly: A rare presentation of splenic angiosarcoma

Mridula Shukla et al. Indian J Med Paediatr Oncol. 2011 Oct.

Abstract

Splenic angiosarcoma is a rare neoplasm that often remains asymptomatic till the onset of massive intra abdominal bleeding that require emergency splenectomy. We report here a case of 60 year old male who presented with on and off fever and a splenomegaly was found on clinical examination suggesting a lymphoproliferative disorder. A contrast enhanced computerized tomography suggested splenic trauma with intracapsular bleed. A splenectomy was carried out that revealed splenic angiosarcoma. Splenomegaly and fever is a very rare presentation of angiosarcoma. Though rare it should be kept in mind when investigating pyrexia of unknown origin.

Keywords: Angiosarcoma; fever; splenomegaly.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Computed tomography scan showing splenic enlargement with subcapsular hematoma
Figure 2
Figure 2
Gross specimen showing the cut surface of the spleen
Figure 3
Figure 3
Photomicrograph showing vascular neoplasm composed of anastomosing vascular channels (H and E, ×100)
Figure 4
Figure 4
Photomicrograph showing a vascular neoplasm composed of anastomosing vascular channels lined by pleomorphic endothelial cells (H and E, ×400)
Figure 5
Figure 5
Photomicrograph showing immunohistochemistry with CD31 showing membranous positivity
See this image and copyright information in PMC

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