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. 2012 Mar-Apr;58(2):197-203.

Differences in body fat distribution assessed by ultrasonography in patients receiving antiretroviral drugs

[Article in English, Portuguese]
Dario Jose Hart Pontes Signorini  1 , Ana Maria Schmidt de Oliveira Netto, Michelle Carreira Miranda Monteiro, Dario Hart Signorini, Cláudia Torres Codeço, Francisco I Bastos, Sergio Gabbay, Marion de Fátima Castro de Andrade
Affiliations
  • PMID: 22569614
Free article

Differences in body fat distribution assessed by ultrasonography in patients receiving antiretroviral drugs

[Article in English, Portuguese]
Dario Jose Hart Pontes Signorini et al. Rev Assoc Med Bras (1992). 2012 Mar-Apr.
Free article

Abstract

Objective: This study aimed to evaluate the body fat content of HIV patients according to the duration of antiretroviral therapy use (DURARV), < 1 year and > 1 year.

Methods: Multiple linear regression was used to investigate the association between ultrasonographic variables of body fat compartments (BFCs) of the face, arm, subcutaneous and visceral abdomen, and the following explanatory variables: gender, age, BMI, and DURARV.

Results: Of all patients (187), 102 of them with DURARV > 1 year were suffering from HIV-related lipodystrophy (HIV-LD), diagnosed through clinical questionnaires. Those with DURARV < 1 year (n = 85, = 46%) did not have HIV-LD. Regarding the visceral compartment, the difference between those with DURARV > 1 year and < 1 year was 11 mm of additional fat content in those with DURARV > 1 year. Women had more fat than men in all peripheral BFCs, while men had 7.2 mm more visceral fat than women, on average.

Conclusion: Ultrasonography is a method capable of measuring the thickness of BFCs and is applicable to clinical practice to diagnose HIV-LD.

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