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Case Reports
. 2011 Oct;12(4):166-8.
doi: 10.4103/1995-705X.90905.

Cardiovascular Complications in Ciguatera Fish Poisoning: A Wake-up Call

Subramanian Senthilkumaran  1 , Ramachandran Meenakshisundaram, Andrew D Michaels, Ponnuswamy Suresh, Ponniah Thirumalaikolundusubramanian
Affiliations
Case Reports

Cardiovascular Complications in Ciguatera Fish Poisoning: A Wake-up Call

Subramanian Senthilkumaran et al. Heart Views. 2011 Oct.

Abstract

Ciguatera fish poisoning occurs with ingestion of fish containing ciguatoxin. It causes a clinical syndrome that comprises classic gastrointestinal, neurological and cardiovascular symptoms. Ciguatoxin is a sodium channel agonist with cholinergic and adrenergic activity. Although cardiovascular symptoms are rare with ciguatoxin, we report two cases with bradycardia and hypotension. Fatality and long-term sequelae are not uncommon with ciguatoxin poisoning and educating the general population is essential.

Keywords: Bradycardia; ciguatoxin; fish poisoning; hypotension.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Electrocardiogram (EKG) of the patient 1
Figure 2
Figure 2
Electrocardiogram (EKG) of the patient 2
See this image and copyright information in PMC

References

    1. Lange W, Lipkin K, Yang G. Can ciguatera be a sexually transmitted disease? J Toxicol Clin Toxicol. 1989;27:193–7. - PubMed
    1. Fasano A, Hokama Y, Russell R, Morris JG., Jr Diarrhea in ciguatera fish poisoning: Preliminary evaluation of pathophysiological mechanisms. Gastroenterology. 1991;100:471–6. - PubMed
    1. Bidard J, Vijverberg H, Frelin C, Chungue E, Legrand AM, Bagnis R, et al. Ciguatoxin is a novel type of Na+ channel toxin. J Biol Chem. 1984;259:8353–7. - PubMed
    1. Geller RJ, Benowitz NL. Orthostatic hypotension in ciguatera fish poisoning. Arch Intern Med. 1992;152:2131–3. - PubMed
    1. Lewis R, Hoy A, McGiffin D. Action of ciguatoxin on human atrial trabeculae. Toxicon. 1992;30:907–14. - PubMed

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