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Comparative Study
. 2012 Nov;53(11):1109-17.
doi: 10.1111/j.1469-7610.2012.02561.x. Epub 2012 May 10.

The Affective Reactivity Index: a concise irritability scale for clinical and research settings

Argyris Stringaris  1 , Robert Goodman, Sumudu Ferdinando, Varun Razdan, Eli Muhrer, Ellen Leibenluft, Melissa A Brotman
Affiliations
Free PMC article
Comparative Study

The Affective Reactivity Index: a concise irritability scale for clinical and research settings

Argyris Stringaris et al. J Child Psychol Psychiatry. 2012 Nov.
Free PMC article

Abstract

Background: Irritable mood has recently become a matter of intense scientific interest. Here, we present data from two samples, one from the United States and the other from the United Kingdom, demonstrating the clinical and research utility of the parent- and self-report forms of the Affective Reactivity Index (ARI), a concise dimensional measure of irritability.

Methods: The US sample (n = 218) consisted of children and adolescents recruited at the National Institute of Mental Health meeting criteria for bipolar disorder (BD, n = 39), severe mood dysregulation (SMD, n = 67), children at family risk for BD (n = 35), or were healthy volunteers (n = 77). The UK sample (n = 88) was comprised of children from a generic mental health setting and healthy volunteers from primary and secondary schools.

Results: Parent- and self-report scales of the ARI showed excellent internal consistencies and formed a single factor in the two samples. In the US sample, the ARI showed a gradation with irritability significantly increasing from healthy volunteers through to SMD. Irritability was significantly higher in SMD than in BD by parent-report, but this did not reach significance by self-report. In the UK sample, parent-rated irritability was differentially related to emotional problems.

Conclusions: Irritability can be measured using a concise instrument both in a highly specialized US, as well as a general UK child mental health setting.

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Figures

Figure 1
Figure 1
(A) Mean ARI score (95% CI) by diagnostic group parent-rated. ‘ns’ denotes no statistically significant differences, sample sizes reflect those with parent-report ARI data available.***p < 0.001, **p < 0.01. HV, healthy volunteers. FRBD, children at family risk for bipolar disorder. BD, children with bipolar disorder. SMD, severe mood dysregulation. (B) Mean ARI score (95% CI) by diagnostic group self-rated. ‘ns’ denotes no statistically significant differences, sample sizes reflect those with self-report ARI data available.***p < 0.001, **p < 0.01. HV, healthy volunteers. FRBD, children at family risk for bipolar disorder. BD, children with bipolar disorder. SMD, severe mood dysregulation
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References

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