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Randomized Controlled Trial
. 2012:2012:498051.
doi: 10.1155/2012/498051. Epub 2012 Apr 22.

Food supplement 20070721-GX may increase CD34+ stem cells and telomerase activity

Po-Cheng Lin  1 , Tzyy-Wen Chiou, Po-Yen Liu, Shee-Ping Chen, Hsin-I Wang, Pi-Chun Huang, Shinn-Zong Lin, Horng-Jyh Harn
Affiliations
Randomized Controlled Trial

Food supplement 20070721-GX may increase CD34+ stem cells and telomerase activity

Po-Cheng Lin et al. J Biomed Biotechnol. 2012.

Abstract

Few rejuvenation and antiaging markers are used to evaluate food supplements. We measured three markers in peripheral blood to evaluate the antiaging effects of a food supplement containing placental extract. Samples were evaluated for CD34(+) cells, insulin-like growth factor 1 (IGF1), and telomerase activity, which are all markers related to aging. To control the quality of this food supplement, five active components were monitored. In total, we examined 44 individuals who took the food supplement from 1.2 months to 23 months; the average number of CD34(+) cells was almost 6-fold higher in the experimental group compared with the control group. Food supplement intake did not change serum IGF1 levels significantly. Finally, the average telomerase activity was 30% higher in the subjects taking this food supplement. In summary, our results suggest that the placental extract in the food supplement might contribute to rejuvenation and antiaging.

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Figures

Figure 1
Figure 1
Effect of 20070721-GX on human rejuvenation. (a) Flow cytometric enumeration of CD34+ hematopoietic stem cells in control and 20070721-GX-treated subjects. (b) Telomerase activity (TRAP assay). (c) Enzyme-linked immunosorbent assay for IGF1. Data represent means ± SEM. Differences between groups were examined by t test. **P < 0.05; ***P < 0.001.
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