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Review
. 2012;8(4):e1002619.
doi: 10.1371/journal.ppat.1002619. Epub 2012 Apr 26.

The role of mast cells in the defence against pathogens

Mirjam Urb  1 , Donald C Sheppard
Affiliations
Review

The role of mast cells in the defence against pathogens

Mirjam Urb et al. PLoS Pathog. 2012.
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Mast cells play a pivotal role in the host defence against pathogens.
Pathogen recognition by host receptors leads to mast cell activation and both direct and indirect antimicrobial responses. Abbreviations: AMP, antimicrobial peptide; CCL20, chemokine (C-C motif) ligand 20; CR, complement receptor; DC, dendritic cell; FcR, Fc receptor; GPI, glycosylphosphatidylinositol; Ig, immunoglobulin; IL-8, interleukin-8; IP10, interferon gamma-induced protein 10; LTC4, leukotriene C4; NK cell, natural killer cell; NOD, nucleotide oligomerisation domain like receptor; ROS, reactive oxygen species; TLR, toll-like receptor; TNF-α, tumour necrosis factor-alpha.
See this image and copyright information in PMC

References

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