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Review
. 2012 Mar;23(3):e48-50.
doi: 10.1258/ijsa.2009.009333.

Spontaneous clearance of chronic hepatitis C infection in a patient with a 20-year-old HIV-hepatitis C co-infection and chronic active hepatitis

R Manfredi  1 , N Dentale, L Calza
Affiliations
Review

Spontaneous clearance of chronic hepatitis C infection in a patient with a 20-year-old HIV-hepatitis C co-infection and chronic active hepatitis

R Manfredi et al. Int J STD AIDS. 2012 Mar.

Abstract

We report a case of spontaneous clearance of hepatitis C virus (HCV) in a patient co-infected for 20 years with HCV and HIV, and with an chronic active hepatitis C never treated with anti-HCV regimens. We review the literature of eight anecdotal reports describing the spontaneous resolution of chronic HCV infection among HIV-infected patients, and discuss the virological, immunological, pathogenetic and therapeutic implications of this observation.

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