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Comment
. 2012 May 15;9(7):368.
doi: 10.1038/nrclinonc.2012.85.

Pancreatic cancer: Mouse models link metabolism and deubiquitination with Kras

Comment

Pancreatic cancer: Mouse models link metabolism and deubiquitination with Kras

Rebecca Kirk. Nat Rev Clin Oncol. .
No abstract available

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Comment on

  • Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
    Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, DePinho RA. Ying H, et al. Cell. 2012 Apr 27;149(3):656-70. doi: 10.1016/j.cell.2012.01.058. Cell. 2012. PMID: 22541435 Free PMC article.
  • The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
    Pérez-Mancera PA, Rust AG, van der Weyden L, Kristiansen G, Li A, Sarver AL, Silverstein KA, Grützmann R, Aust D, Rümmele P, Knösel T, Herd C, Stemple DL, Kettleborough R, Brosnan JA, Li A, Morgan R, Knight S, Yu J, Stegeman S, Collier LS, ten Hoeve JJ, de Ridder J, Klein AP, Goggins M, Hruban RH, Chang DK, Biankin AV, Grimmond SM; Australian Pancreatic Cancer Genome Initiative; Wessels LF, Wood SA, Iacobuzio-Donahue CA, Pilarsky C, Largaespada DA, Adams DJ, Tuveson DA. Pérez-Mancera PA, et al. Nature. 2012 Apr 29;486(7402):266-70. doi: 10.1038/nature11114. Nature. 2012. PMID: 22699621 Free PMC article.

References

    1. Cell. 2012 Apr 27;149(3):656-70 - PubMed
    1. Nature. 2012 Apr 29;486(7402):266-70 - PubMed

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