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Comment
. 2011 Jun;1(1):17-20.
doi: 10.1158/2159-8274.CD-11-0036. Epub 2011 Jun 1.

The BATTLE trial: a bold step toward improving the efficiency of biomarker-based drug development

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Comment

The BATTLE trial: a bold step toward improving the efficiency of biomarker-based drug development

Eric H Rubin et al. Cancer Discov. 2011 Jun.

Abstract

Successful completion of the Biomarker-integrated Approaches of Targeted Therapy for Lung Cancer Elimination (BATTLE) trial, reported in this issue of Cancer Discovery, is an important advance in the effort to improve clinical trial approaches to the simultaneous development of new therapeutics with matching diagnostic tests so that patients most likely to benefit from these therapies can be identified.

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  • The BATTLE trial: personalizing therapy for lung cancer.
    Kim ES, Herbst RS, Wistuba II, Lee JJ, Blumenschein GR Jr, Tsao A, Stewart DJ, Hicks ME, Erasmus J Jr, Gupta S, Alden CM, Liu S, Tang X, Khuri FR, Tran HT, Johnson BE, Heymach JV, Mao L, Fossella F, Kies MS, Papadimitrakopoulou V, Davis SE, Lippman SM, Hong WK. Kim ES, et al. Cancer Discov. 2011 Jun;1(1):44-53. doi: 10.1158/2159-8274.CD-10-0010. Epub 2011 Jun 1. Cancer Discov. 2011. PMID: 22586319 Free PMC article. Clinical Trial.

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