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Comment
. 2012 Jun 12;109(24):E1511; author reply E1512.
doi: 10.1073/pnas.1203463109. Epub 2012 May 15.

Consequences of NMO-IgG binding to aquaporin-4 in neuromyelitis optica

Comment

Consequences of NMO-IgG binding to aquaporin-4 in neuromyelitis optica

Andrea Rossi et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Comment on

References

    1. Hinson SR, et al. Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes. Proc Natl Acad Sci USA. 2012;109:1245–1250. - PMC - PubMed
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    1. Ratelade J, Bennett JL, Verkman AS. Evidence against cellular internalization in vivo of NMO-IgG, aquaporin-4, and excitatory amino acid transporter 2 in neuromyelitis optica. J Biol Chem. 2011;286:45156–45164. - PMC - PubMed
    1. Phuan PW, Ratelade J, Rossi A, Tradtrantip L, Verkman AS. Complement-dependent cytotoxicity in neuromyelitis optica requires aquaporin-4 assembly in orthogonal arrays. J Biol Chem. 2012;287:13829–13839. - PMC - PubMed
    1. Nicchia GP, et al. Aquaporin-4 orthogonal arrays of particles are the target for neuromyelitis optica autoantibodies. Glia. 2009;57:1363–1373. - PubMed

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