3-[(1-Hy-droxy-1-phenyl-propan-2-yl)amino]-5,5-dimethyl-cyclo-hex-2-enone
- PMID: 22590318
- PMCID: PMC3344556
- DOI: 10.1107/S160053681201570X
3-[(1-Hy-droxy-1-phenyl-propan-2-yl)amino]-5,5-dimethyl-cyclo-hex-2-enone
Abstract
The asymmetric unit of the title compound, C(17)H(23)NO(2), consists of two crystallographically independent mol-ecules (A and B). The cyclo-hexene rings in both mol-ecules adopt an envelope conformation. In the crystal, independent mol-ecules, A and B, are each linked by inter-molecular bifurcated (N,O)-H⋯O hydrogen bonds, generating R(2) (1)(7) ring motifs and forming infinite chains along the b axis.
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References
-
- Aghil, O., Bibby, M. C., Carrington, S. J., Douglas, K. T., Phillips, R. M. & Shing, T. K. M. (1992). Anti-Cancer Drug Des. 7, 67–82. - PubMed
-
- Bernstein, J., Davis, R. E., Shimoni, L. & Chang, N.-L. (1995). Angew. Chem. Int. Ed. Engl. 34, 1555–1573.
-
- Bruker (2009). SADABS, APEX2 and SAINT Bruker AXS Inc., Madison, Wisconsin, USA.
-
- Cremer, D. & Pople, J. A. (1975). J. Am. Chem. Soc. 97, 1354–1358.
-
- Ghorab, M. M., Al-Said, M. S. & El-Hossary, E. M. (2011). J. Heterocycl. Chem. 48, 563–571.
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