Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 May 1;68(Pt 5):o1436-7.
doi: 10.1107/S160053681201570X. Epub 2012 Apr 18.

3-[(1-Hy-droxy-1-phenyl-propan-2-yl)amino]-5,5-dimethyl-cyclo-hex-2-enone

3-[(1-Hy-droxy-1-phenyl-propan-2-yl)amino]-5,5-dimethyl-cyclo-hex-2-enone

Mostafa M Ghorab et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

The asymmetric unit of the title compound, C(17)H(23)NO(2), consists of two crystallographically independent mol-ecules (A and B). The cyclo-hexene rings in both mol-ecules adopt an envelope conformation. In the crystal, independent mol-ecules, A and B, are each linked by inter-molecular bifurcated (N,O)-H⋯O hydrogen bonds, generating R(2) (1)(7) ring motifs and forming infinite chains along the b axis.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
The molecular structure of the title compound with atom labels with 30% probability displacement ellipsoids.
Fig. 2.
Fig. 2.
A part of crystal packing of the title compound. The dashed lines represent the hydrogen bonds.

References

    1. Aghil, O., Bibby, M. C., Carrington, S. J., Douglas, K. T., Phillips, R. M. & Shing, T. K. M. (1992). Anti-Cancer Drug Des. 7, 67–82. - PubMed
    1. Bernstein, J., Davis, R. E., Shimoni, L. & Chang, N.-L. (1995). Angew. Chem. Int. Ed. Engl. 34, 1555–1573.
    1. Bruker (2009). SADABS, APEX2 and SAINT Bruker AXS Inc., Madison, Wisconsin, USA.
    1. Cremer, D. & Pople, J. A. (1975). J. Am. Chem. Soc. 97, 1354–1358.
    1. Ghorab, M. M., Al-Said, M. S. & El-Hossary, E. M. (2011). J. Heterocycl. Chem. 48, 563–571.