Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2012 May 17:5:24.
doi: 10.1186/1756-8722-5-24.

Novel therapeutic agents for cutaneous T-Cell lymphoma

Affiliations
Review

Novel therapeutic agents for cutaneous T-Cell lymphoma

Salvia Jain et al. J Hematol Oncol. .

Abstract

Mycosis fungoides (MF) and Sezary Syndrome (SS) represent the most common subtypes of primary Cutaneous T-cell lymphoma (CTCL). Patients with advanced MF and SS have a poor prognosis leading to an interest in the development of new therapies with targeted mechanisms of action and acceptable safety profiles. In this review we focus on such novel strategies that have changed the treatment paradigm of this rare malignancy.

PubMed Disclaimer

References

    1. Bradford PT, Devesa SS, Anderson WF. et al. Cutaneous lymphoma incidence patters in the United States: a population based study of 3884 cases. Blood. 2009;113:5064–5073. doi: 10.1182/blood-2008-10-184168. - DOI - PMC - PubMed
    1. Olsen E, Vonderheid E, Pimpinelli N. et al. Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the international society for cutaneous lymphomas (ISCL) and the cutaneous lymphoma task force of the European organization for research and treatment of cancer (EORTC) Blood. 2007;110:1713–1722. doi: 10.1182/blood-2007-03-055749. - DOI - PubMed
    1. Agar NS, Wedgeworth E, Crichton S. et al. Survival outcomes and prognostic factors in mycosis fungoides/Sezary syndrome: validation of the revised international society for cutaneous lymphomas/European organization for research and treatment of cancer staging proposal. J Clin Oncol. 2010;28:4730–4739. doi: 10.1200/JCO.2009.27.7665. - DOI - PubMed
    1. Kim YH, Liu HL, Mraz-Gernhard S. et al. Long-term outcome of 525 patients with mycosis fungoides and Sezary syndrome: clinical prognostic factors and risk for disease progression. Arch Dermatol. 1996;139:857–866. - PubMed
    1. Horwitz SM, Olsen EA, Duvic M. et al. Review of the treatment of mycosis fungoides and Sezary syndrome: a stage-based approach. J Natl Compr Canc Netw. 2008;6(4):436–442. - PubMed

MeSH terms

Substances

LinkOut - more resources