Structural biology: How opioid drugs bind to receptors
- PMID: 22596150
- PMCID: PMC3589518
- DOI: 10.1038/485314a
Structural biology: How opioid drugs bind to receptors
Abstract
The search for safe, non-addictive versions of morphine and other opioid drugs has just received a boost with the solving of the crystal structures of the receptors to which the drugs bind.
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Comment on
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Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.Nature. 2012 Mar 21;485(7398):321-6. doi: 10.1038/nature10954. Nature. 2012. PMID: 22437502 Free PMC article.
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Structure of the human κ-opioid receptor in complex with JDTic.Nature. 2012 Mar 21;485(7398):327-32. doi: 10.1038/nature10939. Nature. 2012. PMID: 22437504 Free PMC article.
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Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.Nature. 2012 May 16;485(7398):395-9. doi: 10.1038/nature11085. Nature. 2012. PMID: 22596163 Free PMC article.
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Structure of the δ-opioid receptor bound to naltrindole.Nature. 2012 May 16;485(7398):400-4. doi: 10.1038/nature11111. Nature. 2012. PMID: 22596164 Free PMC article.
References
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- Results from the 2009 National Survey on Drug Use and Health: Volume I. Summary of National Findings. Office of Applied Studies; Rockville, MD: 2010.
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