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Case Reports
. 2012 Mar 8:2012:bcr1220115456.
doi: 10.1136/bcr.12.2011.5456.

Successful management of multi-focal hepatic infantile hemangioendothelioma using TACE/surgery followed by maintenance metronomic therapy

Vishal Sondhi  1 , Purna Arun Kurkure, Tushar Vora, Shripad D Banavali, S Vishwanathan, Seema Medhi, Anirudh Kulkarni, Sajid Quereshi, Brijesh Arora
Affiliations
Case Reports

Successful management of multi-focal hepatic infantile hemangioendothelioma using TACE/surgery followed by maintenance metronomic therapy

Vishal Sondhi et al. BMJ Case Rep. .

Abstract

Infantile hepatic hemangioendothelioma (IHE) is a rare angiogenic tumour with diverse clinical presentations and varied course ranging from spontaneous regression to life-threatening complications. The authors report a 2-year boy who presented with respiratory distress and was identified as a case of inoperable multi-focal hepatic IHE. He showed a transient response to trans-arterial-chemo-embolisation and liver resection but had progressive disease despite chemotherapy (prednisolone/vicristine/ifosfamide/cisplatin). Thereafter, he was successfully managed with metronomic therapy using cyclophosphamide and tamoxifen.

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Conflict of interest statement

Competing interests None.

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