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Case Reports
. 2012 May 8:2012:bcr1120115180.
doi: 10.1136/bcr.11.2011.5180.

Rosuvastatin-induced pemphigoid

Aizuri A Murad  1 , Maureen Connolly, Anne-Marie Tobin
Affiliations
Case Reports

Rosuvastatin-induced pemphigoid

Aizuri A Murad et al. BMJ Case Rep. .

Abstract

Statins are widely prescribed medications and very well tolerated. Rosuvastatin is another member of this drug used to treat dyslipidaemia. It is a competitive inhibitor of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase. Immunobullous disease is usually idiopathic but can be drug-induced. Both idiopathic and iatrogenic forms share common clinical and immunohistological features. The authors report a case of pemphigoid induced by rosuvastatin, a commonly prescribed medication. To our knowledge, there is limited report on rosuvastatin associated with pemphigoid in the literature.

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Conflict of interest statement

Competing interests None.

Figures

Figure 1
Figure 1
Scattered intact blisters with erythematous base on mid-anterior thighs. Older blisters seen on her upper calf.
Figure 2
Figure 2
Skin biopsy with H&E staining showed subepidermal blistering (arrow) with chronic inflammatory cell infiltrate perivascularly and in the interstitial spaces.
See this image and copyright information in PMC

References

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