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. 1979 May 1;179(2):441-4.
doi: 10.1042/bj1790441.

Are polyphosphoinositides associated with glycophorin in human erythrocyte membranes?

S D Shukla, R Coleman, J B Finean, R H Michell

Are polyphosphoinositides associated with glycophorin in human erythrocyte membranes?

S D Shukla et al. Biochem J. .

Abstract

Glycophorin prepared by a lithium di-iodosalicylate-extraction/phenol-partition method was rich in polyphosphoinositides (phosphatidyl-myo-inositol 4-phosphate and phosphatidyl-myo-inositol 4,5-bisphosphate), but glycophorin extracted by Triton X-100 showed no such enrichment. The enrichment observed in the former preparations appeared not to be caused by pre-existing association between glycophorin and polyphosphoinositides in the human erythrocyte membrane, but to be largely a consequence of the preparative procedures.

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