Arterial emboli complicating Cisplatin therapy
- PMID: 22606452
- PMCID: PMC3350183
- DOI: 10.1155/2012/276385
Arterial emboli complicating Cisplatin therapy
Abstract
We report three cases of arterial emboli in patients with lung cancer treated with cisplatin chemotherapy. All three patients were managed without surgical intervention but subsequent oncological treatment was complicated by the sequelae of arterial emboli. We discuss the issues surrounding these patients and the importance of identifying patients at risk of arterial embolic phenomena with cisplatin treatment.
References
-
- Cisplatin. British National Formulary Website, 2011, http://bnf.org/bnf/bnf/current/67743.htm.
-
- Numico G, Garrone O, Dongiovanni V, et al. Prospective evaluation of major vascular events in patients with nonsmall cell lung carcinoma treated with cisplatin and gemcitabine. Cancer. 2005;103(5):994–999. - PubMed
-
- Licciardello JTW, Moake JL, Rudy CK. Elevated plasma von Willebrand factor levels and arterial occlusive complications associated with cisplatin-based chemotherapy. Oncology. 1985;42(5):296–300. - PubMed
-
- Talcott JA, Herman TS. Acute ischemic vascular events and cisplatin. Annals of Internal Medicine. 1987;107(1):121–122. - PubMed
-
- Bick RL. Cancer-associated thrombosis. New England Journal of Medicine. 2003;349(2):109–111. - PubMed
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