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. 2012 Nov;126(5):356-62.
doi: 10.1111/j.1600-0447.2012.01874.x. Epub 2012 May 21.

Rumination, gender, and depressive symptoms associated with caregiving strain in bipolar disorder

Affiliations

Rumination, gender, and depressive symptoms associated with caregiving strain in bipolar disorder

D A Perlick et al. Acta Psychiatr Scand. 2012 Nov.

Abstract

Objective: To evaluate the associations between indices of caregiving strain, ruminative style, depressive symptoms, and gender among family members of patients with bipolar disorder.

Method: One hundred and fifty primary caregivers of patients enrolled in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) participated in a cross-sectional study to evaluate the role of ruminative style in maintaining depressive symptoms associated with caregiving strain. Patient lifetime diagnosis and current episode status were evaluated by the Affective Disorder Evaluation and the Clinical Monitoring Form. Caregivers were evaluated within 30 days of the patient on measures of family strain, depressive symptoms, and ruminative style.

Results: Men and women did not differ on depression, caregiver strain, or ruminative style scores. Scores suggest an overall mild level of depression and moderate caregiver strain for the sample. Greater caregiver strain was significantly associated (P<0.05) with rumination and level of depressive symptoms, controlling for patient clinical status and demographic variables. Rumination reduced the apparent association between strain and depression by nearly half. Gender was not significantly associated with depression or rumination.

Conclusion: Rumination helps explain depressive symptoms experienced by both male and female caregivers of patients with bipolar disorder. Interventions for caregivers targeted at decreasing rumination should be considered.

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Conflict of interest statement

Declaration of Interest

Dr. Calabrese has received grant support, lecture honoraria, or has participated in advisory boards with Abbott, AstraZeneca, Bristol-Myers Squibb/Otsuka, Cephalon, Dainippon Sumitomo, Forest, France Foundation, GlaxoSmithKline, Janssen, Johnson and Johnson, Lilly, Lundbeck, Merck, Neurosearch, OrthoMcNeil, Pfizer, Repligen, Sanofi, Schering-Plough, Servier, Solvay, Synosia, Supernus Pharmaceuticals, Takeda and Wyeth. Dr. Huth received grant support from Michigan State University. Each of the other authors declares no conflict of interest.

Figures

Fig. 1
Fig. 1
Mediational effect of rumination on depression. Numbers represent standardized beta coefficients, after controlling for caregiver age, caregiver SES, and patient clinical status. *P < 0.05, **P < 0.01, ***P < 0.001.

References

    1. Perlick D, Clarkin JF, Sirey J, et al. Burden experienced by caregivers of persons with bipolar affective disorder. Br J Psychiatry. 1999;174:56–62. - PubMed
    1. Reinares M, Vieta E. The burden on the family of bipolar patients. Clin Approach in Bipolar Disord. 2004;3:17–23.
    1. Ostacher MJ, Nierenberg AA, Iosifescu DV, et al. Correlates of subjective and objective burden among caregivers of patients with bipolar disorder. Acta Psychiatr Scand. 2008;118:49–56. - PubMed
    1. Struening EL, Stueve A, Vine P, Kreisman DE, Link BG, Herman DB. Factors associated with grief and depressive symptoms in caregivers of people with serious mental illness. Res Commun Mental Health. 1995;8:91–124.
    1. Perlick DA, Rosenheck RA, Miklowitz DJ, et al. Caregiver burden and health in bipolar disorder: a cluster analytic approach. J Nerv Ment Dis. 2008;196:484–491. - PMC - PubMed

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