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. 2012 Jun;18(6):998-1001.
doi: 10.3201/eid1806.110997.

Wild boars as hosts of human-pathogenic Anaplasma phagocytophilum variants

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Wild boars as hosts of human-pathogenic Anaplasma phagocytophilum variants

Jerzy Michalik et al. Emerg Infect Dis. 2012 Jun.

Abstract

To investigate the potential of wild boars to host Anaplasma phagocytophilum, we analyzed bacterial 16S rRNA and ank genes. DNA sequencing identified several A. phagocytophilum variants, including a predominance of strains known to cause human disease. Boars are thus hosts for A. phagocytophilum, notably, strains associated with human granulocytic anaplasmosis.

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Figures

Figure 1
Figure 1
Phylogenetic relationships based on Anaplasma phagocytophilum 16S rRNA gene fragment sequences obtained from wild boars and engorged Ixodes ricinus ticks and selected sequences from GenBank. The scale bar indicates an evolutionary distance of 0.001 nt per position in the sequence. Inference was made by using the neighbor-joining algorithm method (Vector NTI Advance 10.3.0; Invitrogen Corp., Carlsbad, CA, USA).
Figure 2
Figure 2
Phylogenetic relationships based on Anaplasma phagocytophilum ankA gene fragment sequences obtained from wild boars and engorged Ixodes ricinus ticks and selected sequences from GenBank. The scale bar indicates an evolutionary distance of 0.001 nt per position in the sequence. Inference was made by using the neighbor-joining algorithm method (Vector NTI Advance 10.3.010.3.0; Invitrogen Corp., Carlsbad, CA, USA).

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References

    1. Woldehiwet Z. The natural history of Anaplasma phagocytophilum. Vet Parasitol. 2010;167:108–22. 10.1016/j.vetpar.2009.09.013 - DOI - PubMed
    1. Massung RF, Mauel MJ, Owens JH, Allan N, Courtney JW, Stafford KC III, et al. Genetic variants of Ehrlichia phagocytophila, Rhode island and Connecticut. Emerg Infect Dis. 2002;8:467–72. 10.3201/eid0805.010251 - DOI - PMC - PubMed
    1. de la Fuente J, Massung RF, Wong SJ, Chu FK, Lutz H, Meli M, et al. Sequence analysis of the msp4 gene of Anaplasma phagocytophilum strains. J Clin Microbiol. 2005;43:1309–17. 10.1128/JCM.43.3.1309-1317.2005 - DOI - PMC - PubMed
    1. Scharf W, Schauer S, Freyburger F, Petrovec M, Schaarschmidt-Kiener D, Liebisch G, et al. Distinct host species correlate with Anaplasma phagocytophilum ankA gene clusters. J Clin Microbiol. 2011;49:790–6. 10.1128/JCM.02051-10 - DOI - PMC - PubMed
    1. Johansson K-E, Pettersson B, Uhle’n M, Gunnarsson A, Malmqvist M, Olsson E. Identification of the causative agent of granulocytic ehrlichiosis in Swedish dogs and horses by direct solid phase sequencing of PCR products from the 16S rRNA gene. Res Vet Sci. 1995;58:109–12. 10.1016/0034-5288(95)90061-6 - DOI - PubMed

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