Local transmission of imported endemic syphilis, Canada, 2011
- PMID: 22607961
- PMCID: PMC3358156
- DOI: 10.3201/eid1806.111421
Local transmission of imported endemic syphilis, Canada, 2011
Abstract
Endemic (nonvenereal) syphilis is relatively common in nonindustrialized regions of the world. We describe a case of local transmission in Canada and review tools available for confirming a diagnosis. Improved molecular tools and global clinical awareness are needed to recognize cases of endemic syphilis imported to areas where it is not normally seen.
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References
-
- Endemic treponematoses in the 1980s [editorial]. Lancet. 1983;2:551–2. - PubMed
-
- Kapembwa MS. Endemic treponematoses. In: Cook GC, Zumla A, editors. Manson’s tropical diseases. New York: Elsevier; 2009. p. 1139–48.
-
- Yakinci C, Ozcan A, Aslan T, Demirhan B. Bejel in Malatya, Turkey. J Trop Pediatr. 1995;41:117–20. - PubMed
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