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Review
. 2012 Oct 9;413(19-20):1583-90.
doi: 10.1016/j.cca.2012.05.009. Epub 2012 May 16.

Interleukin 6 and C-reactive protein in esophageal cancer

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Review

Interleukin 6 and C-reactive protein in esophageal cancer

Magdalena Groblewska et al. Clin Chim Acta. .

Abstract

Esophageal cancer (EC) is one of the most aggressive malignant tumors of the gastrointestinal tract. It is well known that cancer initiation and tumor development are closely linked with inflammation. C-reactive protein (CRP) and interleukin-6 (IL-6) are acute-phase proteins involved in cancer development. It was suggested that CRP and IL-6 play potential roles in the growth and progression of malignant tumors, including EC. The aim of the study was to describe the significance of IL-6 and CRP in the development of esophageal cancer and to assess the potential role of their serum levels as prognostic indicators of EC patient's survival.

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