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. 2012 Sep;83(6):1072-5.
doi: 10.1016/j.fitote.2012.05.005. Epub 2012 May 17.

Norditerpenoids from Salvia castanea Diels f. pubescens

Zheng-Hong Pan  1 , Yan Li, Xing-De Wu, Juan He, Xuan-Qin Chen, Gang Xu, Li-Yan Peng, Qin-Shi Zhao
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Norditerpenoids from Salvia castanea Diels f. pubescens

Zheng-Hong Pan et al. Fitoterapia. 2012 Sep.

Abstract

Three new norditerpenoids, castanol A-C (1-3), along with eighteen known diterpenoids, were isolated from Salvia castanea Diels f. pubescens. Their structures were elucidated by extensive spectroscopic analysis. All compounds were evaluated for their cytotoxic activities against five human cancer cell lines. The known compounds neo-tanshinlactone (12) and methyltanshinoate (17) exhibited significant cytotoxic activities against some cells.

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